MEMPHIS: Virginia boy 'looks good' after receiving new drug - WRBL

Doctors: Virginia boy 'looks good' after receiving experimental drug

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Josh Hardy, 7, is hospitalized at St. Jude Children's Research Hospital in Memphis with an adenovirus infection. Josh Hardy, 7, is hospitalized at St. Jude Children's Research Hospital in Memphis with an adenovirus infection.
RALEIGH, N.C. -

A 7-year-old Virginia boy whose life depends on anexperimental anti-viral drug made in Research Triangle Park is tolerating hisfirst treatment well, doctors say.

Josh Hardy is hospitalized at St. Jude Children's ResearchHospital in Memphis with an adenovirus infection. With his heart and kidneysfailing, doctors gave Josh just two weeks to live, but Durham-based Chimerixhas a new drug that could save his life.

Chimerix announced Tuesday that it had reached agreementwith the United States Food and Drug Administration to immediately begintreating Josh with the drug brincidofovir.

Doctors at St. Jude began administering the drug Wednesdayaround 10 p.m.

His doctors describe Josh as "a very sick little boy," butsay he tolerated the drug well and he looks good today.

Josh's doctors call the drug therapy a marathon, not asprint. It will take time to determine if the medication will save him.

The administering of the drug came after Josh's family wagedan extensive public campaign, Chimerix CEO Kenneth Moch said.

"There is no doubt that the social media aspects ofthis helped to accelerate what had been an on-going dialog with the FDA,"Moch said.

Moch said Josh is receiving the drug as part of the lastphase of clinical test to be run on brincidofovir. It has taken 14 years todevelop the drug to this point, and Moch said the earliest the drug could go onthe market is 2016.

Moch said Josh will be the first patient in a pilot trial ofbrincidofovir. Nineteen others will also be given the drug as part of the lastround of the clinical testing for the drug.

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