UPDATE: 6/15/22 7:16 pm CST

A family member tells News 3, that his paralyzed mother-in-law was trapped inside the home during the fire, but her husband was able to make it out. The family member says the fire started in the kitchen.

News 3 has not been able to confirm this with the coroner or fire departments on the scene as they are still actively working.

UPDATE: 6/15/22 7:01 pm CST

Traffic is slowly moving in both directions using one lane.

PHENIX CITY, Ala. (WRBL) – Multiple first responders are on the scene of an apparent house fire on Hwy 165 in Phenix City. At least a dozen fire trucks and first responders are on the scene in the mutual aid call. The location of the fire is across the roadway from AE Fuels, that area is off of Hwy 165 between Sunderland Drive and Miller Road.

Smoke can be seen billowing in the air.

Hwy 165 is blocked in both directions near the scene of the incident.

Information about possible injuries is not available at this time.

Fire crews on scene include Uchee Volunteer Fire Department, Phenix City Fire and Rescue, Fort Mitchell Fire Department, and Seale Volunteer Fire Department.

This is a developing story. Stay with WRBL News 3 on-air and online for new details as they become available.